Assessment of Some Hematological and Biochemical Parameters of Diesel Generator Workers in Al-Diwaniyah Province, Iraq
DOI:
https://doi.org/10.21070/ijhsm.v2i1.157Keywords:
Study, Hematological, Biochemical Parameters, Diesel Generator, Al-DiwaniyahAbstract
Background: Continuous exposure to pollutants from diesel generators may cause numerous health problems. The current study aimed to determine the effects of diesel generators on workers by examining hematological and biochemical parameters. Methods: The current study was conducted on diesel generator workers in Al-Qadisiyah Governorate. The study consisted of approximately (50) individuals divided into two groups: the first group (25) workers, and the second group (25) healthy individuals (as a control group). The parameters studied included blood parameters (red blood cells, hemoglobin, and pneumococcal size), as well as biochemical tests, including liver function tests (AST, ALT, and ALP), and kidney function tests, including (urea, creatinine, and total protein). Results: The results indicated significant changes (P<0.05) in biochemical parameters. There was a significant increase (P<0.05) in red blood cell count, hemoglobin, pneumococcal volume, liver function tests (ALT, ALP, AST), urea-creatinine, total cholesterol, and triglycerides. The study results also showed a significant decrease (P<0.05) in total protein concentration in generator workers when compared to the healthy group. Conclusion: Direct exposure to pollutants by generator workers may lead to changes in their blood and biochemical parameters because it targets important sites in the body, especially the bone marrow, kidneys, liver, and other organs.
Highlights:
-
Diesel generator workers exhibit significant alterations in hematological and biochemical parameters compared to the control group.
-
Exposure to generator pollutants increases red blood cell count, liver enzymes (ALT, AST, ALP), and kidney markers (urea, creatinine).
-
Reduced total protein levels highlight the adverse effects of prolonged pollutant exposure on overall health.
Keywords : Study, Hematological, Biochemical Parameters, Diesel Generator, Al-Diwaniyah
References
[1] M. A. Al-Eed, F. N. Assubaie, M. M. EL-Garawany, H. EL-Hamshary, and Z. M. EI-Tayeb, “Determination of Heavy Metal Levels in Common Spices,” Department of Botany, College of Agriculture and Food Sciences, King Faisal University, Saudi Arabia, pp. 2, 1997.
[2] R. Carletti and D. Romano, “Assessing Health Risk From Benzene Pollution in an Urban Area,” Environmental Monitoring and Assessment, vol. 80, pp. 135–148, 2002.
[3] Fucikova, A. Slamova, J. Szakova, J. Cibulka, and J. Heger, “The Influence of Dietary Cadmium on Hematological Parameters and Phagocytic Activity of Leukocytes in Rats,” Zivocisna Vyroba, vol. 40, no. 1, pp. 15–18, 1995.
[4] N. A. A. Al-Fahadi, “A Comparative Study of the Effect of Carbon Monoxide, Lead, and Cadmium on Workers in Contact with These Pollutants,” Ph.D. dissertation, Faculty of Science, University of Mosul, Iraq, 2002.
[5] M. J. M. Al-Hamish, R. A. Abdul-Jabbar, and S. M. R. Al-Obaidi, “Contamination of the Blood of Workers in the Fertilizer Industry With Heavy Elements,” Journal of Education and Science, vol. 19, no. 2, p. 15, 2007.
[6] P. Péter, F. Ferenc, Á. B. Ákos, and B. László, “Accumulation of Some Heavy Metals (Pd, Cd, and Cr) in Milk of Grazing Sheep in Northeast Hungary,” Journal of Microbiology, Biotechnology and Food Sciences, vol. 2, no. 1, pp. 389–394, 2012.
[7] A. Shabib and M. Q. Al-Ani, “Study of Dummy Variables in Ramadi Fuel Filling Stations,” Anbar University Journal of Pure Sciences, vol. 8, no. 1, pp. 1–8, 2014.
[8] M. Horiguchi, M. Sato, N. Konno, and M. Fukushima, “Long-Term Cadmium Exposure Induces Anemia in Rats Through Hypoproduction of Erythropoietin in the Kidneys,” Archives of Toxicology, vol. 71, pp. 11–19, 1996.
[9] S. H. Fadel, K. F. Abdul-Ghafour, and A. Fadam, “Estimating the Concentrations of Some Heavy Elements and Studying Some Hematological Variables in the Blood of Workers in Diesel Generators in the City of Ramadi,” Anbar University Journal of Pure Sciences, vol. 7, no. 1, pp. 1–7, 2013.
[10] M. L. Caspers and G. J. Sigel, “Inhibition by Lead of Human Erythrocyte (Na+-K+) Adenosine Triphosphatase Associated with Binding of Pb210 to Membrane Fragment,” Biochimica et Biophysica Acta, vol. 600, pp. 27–32, 1980.
[11] D. G. Penny, A. Giraldo, and E. M. Van Egmond, “Chronic Carbon Monoxide Exposure in Young Rats Alters Coronary Vessel Growth,” Journal of Toxicology and Environmental Health, vol. 39, pp. 207–222, 1983.
[12] S. Clarissa, F. Andréa, R. Leandro, R. Jurandir, W. Jez, and G. José, “Toxic Metals (Pb and Cd) and Their Respective Antagonists (Ca and Zn) in Infant Formulas and Milk Marketed in Brasilia, Brazil,” International Journal of Environmental Research and Public Health, vol. 7, pp. 4062–4077, 2010.
[13] N. A. Zidan, “Hepatotoxicity and Nephrotoxicity of Pesticides,” Assiut Journal of Environmental Studies, pp. 65–91, 2010.
[14] F. Zilva, P. Pannall, and P. D. Mayre, Clinical Chemistry in Diagnosis and Treatment, 5th ed. Stoughton: Edward Arnold, pp. 14–16, 1989.
[15] Serif, G. Alper, Ö. Abdullah, O. Kurtulus, Y. Türker, K. Emel, and A. Emel, “The Effect of Benzene on Serum, Hepatic, and Renal Glutathione S-Transferase, Superoxide Dismutase, and Catalase of Rat and Rabbit,” Biochemical Archives, vol. 15, pp. 239–246, 1999.
[16] P. Chowdhury and D. Louria, “Influence of Cadmium and Other Trace Metals on Human Beta-Antitrypsin: An In Vitro Study,” Science, vol. 191, pp. 480–481, 1976.
[17] B. J. Sharkey, Fitness & Health, 4th ed. Champaign, IL: Human Kinetics, 1997.
[18] D. E. Vance and J. E. Vance, Biochemistry of Lipids, Lipoproteins, and Membranes. New York: Elsevier Science, 1996.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Ali Abdul Ameer Al Anbaki
This work is licensed under a Creative Commons Attribution 4.0 International License.
