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Triglyceride and Blood Glucose Levels in Diabetic Smokers and Non-Smokers

Tingkat Trigliserida dan Gula Darah pada Penderita Diabetes yang Merokok dan yang Tidak Merokok
Vol. 2 No. 2 (2025): Oktober:
DOI : https://doi.org/10.21070/ijhsm.v2i2.227
Published : Aug 20, 2025

Mayang Riantika (1), Andika Aliviameita (2)

(1) Program Studi Teknologi Laboratorium Medis, Universitas Muhammadiyah Sidoarjo, Indonesia
(2) , Indonesia
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Abstract:

General background: Diabetes Mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia and dyslipidemia, which often worsens with unhealthy lifestyle habits. Specific background: Smoking introduces toxic substances such as nicotine that can alter lipid metabolism, insulin sensitivity, and glucose regulation, thereby potentially aggravating complications in diabetic patients. Knowledge gap: While dyslipidemia and hyperglycemia in diabetes are well documented, evidence on the comparative differences between smokers and non-smokers with diabetes remains limited. Aim: This study investigated the differences in triglyceride and blood glucose levels among diabetic patients who smoke and those who do not. Results: An experimental design was conducted at Anna Medika Hospital Madura with 30 participants (15 smokers and 15 non-smokers with diabetes). The Mann Whitney test showed significant differences in triglyceride levels (p=0.000) and blood glucose levels (p=0.049) between the two groups, with smokers displaying higher values. Novelty: This study highlights nicotine’s role in exacerbating lipid and glucose dysregulation in diabetes within an Indonesian hospital setting. Implications: Findings emphasize the importance of targeted lifestyle interventions and smoking cessation programs in managing metabolic control among diabetic patients.


 


Highlights:



  1. Smokers with diabetes had higher triglyceride and glucose levels.

  2. Nicotine worsens insulin resistance and lipid metabolism.

  3. Lifestyle modification is crucial for better diabetes management.


Keywords: Diabetes Mellitus, Smoking, Triglycerides, Blood Glucose, Lifestyle

References

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[3] World Health Organization (WHO), “Data Diabetes Mellitus,” WHO, 2021.

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