Nibras abud al Aziz Hamood (1)
The current study investigates the prevalence of Trichomonas vaginalis in women visiting Samarra General Hospital between August 2023 and June 2024. A total of 325 samples were examined from women aged 19 to 51 years, with an infection rate of 2.34%. The highest infection rate was observed in the 30-40 age group, among women experiencing itching during menstruation (4.16%), those with white vaginal discharge (2.97%), and infertile women (4.16%). The infection rate was higher among rural women (3.57%) compared to urban residents.
Regarding trace elements, the study recorded a significant decrease in serum zinc and iron levels in infected women (p < 0.01) compared to the control group. However, no significant difference was observed in lead concentrations, with levels recorded as 2.83 µg/dl and 2.62 µg/dl in infected and control groups, respectively.
Additionally, antioxidant levels showed a notable decline in infected women:
Highlights:
Keywords: Trichomonas vaginalis, prevalence, trace elements, antioxidants, infection rate
. G. Virella, Microbiology and Infections Disease, 3rd ed. Williams and Wilkins, USA, 1997.
. A. Pillitteri, Maternal and Child Health Nursing, 3rd ed. Lippincott, New York, 1999.
. World Health Organization, Drugs Used in Parasitic Diseases, 2nd ed., Geneva, Switzerland, 1995, pp. 2-27.
. J. Ryu, H. Choi, and D. Min, "Effect of iron on the virulence of Trichomonas vaginalis," Journal of Parasitology, vol. 87, pp. 457-460, 2001.
. C. A. Burtis, R. A. Ashwood, and E. Bruns, Tietz Fundamentals of Clinical Chemistry, Elsevier, 2008.
. S. L. Dorris and R. S. Peebles, "PGI2 as a regulator of inflammatory diseases," Mediators of Inflammation, vol. 2012, p. 926968, 2012.
. H. K. Ghneim and M. M. Alshebly, "Biochemical markers of oxidative stress in Saudi women with recurrent miscarriage," Journal of Korean Medical Science, vol. 1, pp. 98-105, 2016.
. S. Ghosh, Paniker’s Textbook of Medical Parasitology, 8th ed., Jaypee Brothers Medical Publishers, India, 2018, p. 256.
. E. Sarıkaya and S. Dogan, "Glutathione peroxidase in health and diseases," in Glutathione System and Oxidative Stress in Health and Disease, 2020, p. 49.
. A. S. Sastry and S. Bhat, Essentials of Medical Parasitology, 1st ed., Jaypee Brothers Medical Publishers Pvt. Ltd., Bangladesh, 2014, p. 356.
. R. G. Schlienger and C. R. Meier, "Effect of selective serotonin reuptake inhibitors on platelet activation: Can they prevent acute myocardial infarction?" American Journal of Cardiovascular Drugs, vol. 3, no. 3, pp. 149–162, 2003.
. X. Zhang, J. Zhang, X. Yang, and X. Han, "Several transcription factors regulate COX-2 gene expression in pancreatic beta-cells," Molecular Biology Reports, vol. 34, pp. 199-206, 2007.
. A. Shehabi, Z. Awwad, M. Al-Ramahi, et al., "Detection of Mycoplasma genitalium and Trichomonas vaginalis infections," 2009.
. M. Matini, S. Rezaie, M. Mohebali, A. H. Maghsood, S. Rabiee, M. Fallah, and M. Rezaeian, "Prevalence of Trichomonas vaginalis infection in Hamadan City, Western Iran," Iranian Journal of Parasitology, 2012.
. T. E. Gorrell, N. Yarlett, and M. Muller, "Isolation and characterization of Trichomonas vaginalis ferredoxin," Carlsberg Research Communications, vol. 49, pp. 259-268, 1984.
. E. Özdemir, N. Keleştemur, and M. Kaplan, "Trichomonas vaginalis as a rare cause of male factor infertility at a hospital in East Anatolia," Andrologia Journal, vol. 43, no. 4, pp. 283-285, 2011.
. P. Demes, A. Gombosova, M. Valent, H. H. Fabusova, and A. Janoska, "Fewer Trichomonas vaginalis organisms in vaginas of infected women during menstruation," Genitourinary Medicine, vol. 64, pp. 22-24, 1988.
. A. Khalaf, S. Al-Asadi, A. Al-Yaaqub, and S. Al-Mayah, "Use of PCR technique to detect Trichomonas vaginalis among men in Basrah province," TQMJ, vol. 4, no. 2, pp. 29-36, 2010.
. M. Rezaeian, M. Vatanshenassan, S. Rezaie, N. Niromand, and Z. Babaei, "Prevalence of Trichomonas vaginalis using parasitologic methods in Tehran," Iranian Journal of Parasitology, vol. 4, no. 4, pp. 43-47, 2009.
. S. A. Kadhum, "Epidemiological study of Trichomonas vaginalis in married women," Proceedings of the Eleventh Veterinary Scientific Conference, pp. 293-298, 2012.
. J. Mishra, S. Carpenter, and S. Singh, "Low serum zinc levels in an endemic area of visceral leishmaniasis in Bihar, India," Journal of Medical Research, vol. 131, pp. 793-798, 2010.
. R. T. Ibrahim, "Study of estrogen, progesterone, copper, zinc, and some antioxidants in sera of ovarian cancer patients," Rafidain Journal of Science, vol. 24, no. 5, pp. 64-71, 2013.
. A. H. Shanker and A. S. Prasad, "Zinc and immune function: The biological basis of altered resistance to infection," American Journal of Clinical Nutrition, vol. 68, pp. 447S-463S, 1998.
. E. W. Murphy, B. W. Willis, and B. K. Watt, "Provisional tables on the zinc of food," Journal of the American Dietetic Association, vol. 66, pp. 345-355, 1975.
. I. G. Y. Al-Ubaidi, "Epidemiological and immunological study of women infected with Trichomonas vaginalis in Tikrit and Baiji," Master's thesis, College of Education, University of Tikrit, 2010.
. S. A. W. Saba and N. K. M. Jawad, "Trace elements levels in patients with some different parasitic infections," Journal of the Bahrain Medical Society, vol. 21, no. 4, 2009.
. R. Sehgal, K. Goyal, and A. Sehgal, "Trichomoniasis and lactoferrin: Future prospects," Infectious Diseases in Obstetrics and Gynecology, vol. 2012, article ID 536037, 8 pages, 2012.