Assessment of Cardiac Effect of Preeclampsia. Right Ventricular Function Analysis Using Speckle Tracking Echocardiography

• Manal Yahya I. AL- Muhana

  Karbala health department, Karbala

• Amina A B AL Dujeli

  Facility of medicine\university of Kufa

Introduction, Preeclampsia is a hypertensive disorder of pregnancy that has significant implications for cardiac function, particularly on the right ventricle (RV). Research has shown that speckle tracking echocardiography (STE) is a valuable tool in evaluating subtle RV dysfunction that might not be detected by traditional methods. Method: Pregnant ladies with preeclampsia (n= 50) compare to normotensive pregnant women (n= 50) regarded as control. Echocardiography done for them by speckle tracking to evaluate function of right ventricle.  Result: There was significant difference in right ventricular function, in right ventricular longitudinal strain from normotensive pregnant women by speckle tracking echo cardio graph (-16.1±2.05 vs -17.3±1.9). Conclusion: Hypertensive disease of pregnancy including preeclampsia affect the myocardial performance, this can be diagnosed by decrease in global longitudinal strain of right ventricle by speckle tracking echocardiography.

Highlights:

1. Preeclampsia affects right ventricular function, detectable via speckle tracking echocardiography.
2. Compared 50 preeclamptic and 50 normotensive pregnant women using echocardiography.
3. Reduced right ventricular longitudinal strain in preeclampsia (-16.1±2.05 vs -17.3±1.9).

Keywords: preeclampsia, speckle tracking echocardiography, right ventricle, global longitudinal strain

H. M. A. Al-Allak and A. H. N. Al-Aboodi, "Assessment of Left Atrial Phasic Volumes and Functions During Third Trimester of Healthy Pregnancy," J. Pioneering Med. Sci., vol. 12, pp. 6–11, 2023.

E. H. M. Al-Obaidi and A. H. N. Al-Aboodi, "The Effect of Age on Right Ventricular Systolic Function Using Traditional Echocardiographic Measures," Kufa Med. J., vol. 20, pp. 97–104, 2024.

H. Alimi, A. Fazlinejad, M. Emadzadeh, and M. Abouzari, "Investigating the Relationship Between Right Ventricular Size and Function With Pre‐Eclampsia: A Two‐Group Cross‐Sectional Study," Health Sci. Rep., vol. 6, p. e1135, 2023.

F. Ancona et al., "Right Ventricular Systolic Function in Severe Tricuspid Regurgitation: Prognostic Relevance of Longitudinal Strain," Eur. Heart J.-Cardiovasc. Imaging, vol. 22, pp. 868–875, 2021.

A. Bülez, K. Hansu, E. Çağan, A. Şahin, and H. Dokumacı, "Artificial Intelligence in Early Diagnosis of Preeclampsia," Niger. J. Clin. Pract., vol. 27, pp. 383–388, 2024.

H. E. Collins et al., "Guidelines for Assessing Maternal Cardiovascular Physiology During Pregnancy and Postpartum," Am. J. Physiol.-Heart Circ. Physiol., 2024.

H. M. A. O. Elham and A.-A. Asaad Hasan Noaman, "Using Speckle Tracking Analysis, Does Age Affect RV Longitudinal Strain?," J. Prev. Diagn. Manage Hum. Dis., vol. 4, pp. 29–38, 2024.

M. H. Hassan, A. E. Hamid, A. O. Abdel-Motaal, and H. A. Mahmoud, "Assessment of RV Systolic Function by Two-Dimensional Speckle Tracking Echocardiography in Patients With Preeclampsia Before and After Labor," Egypt. J. Hosp. Med., vol. 76, pp. 3924–3932, 2019.

L. H. Joubert et al., "Cardiac Magnetic Resonance Imaging in Preeclampsia Complicated by Pulmonary Edema Shows Myocardial Edema With Normal Left Ventricular Systolic Function," Am. J. Obstet. Gynecol., vol. 227, pp. 292.e1–292.e11, 2022.

S. A. Karrar, D. J. Martingano, and P. L. Hong, "Preeclampsia," StatPearls [Internet]. StatPearls Publishing, 2024.

J. M. Kazma, J. Van Den Anker, K. Allegaert, A. Dallmann, and H. K. Ahmadzia, "Anatomical and Physiological Alterations of Pregnancy," J. Pharmacokinet. Pharmacodyn., vol. 47, pp. 271–285, 2020.

A. Paudel et al., "The Evaluation of Ventricular Functions by Speckle Tracking Echocardiography in Preeclamptic Patients," Int. J. Cardiovasc. Imaging, vol. 36, pp. 1689–1694, 2020.

V. Regitz-Zagrosek et al., "2018 ESC Guidelines for the Management of Cardiovascular Diseases During Pregnancy: The Task Force for the Management of Cardiovascular Diseases During Pregnancy of the European Society of Cardiology (ESC)," Eur. Heart J., vol. 39, pp. 3165–3241, 2018.

M. Tadic et al., "Blood Pressure Variability Correlates With Right Ventricular Strain in Women With Gestational Hypertension and Preeclampsia," J. Hum. Hypertens., vol. 36, pp. 826–832, 2022.

M. S. Tanner, M.-A. Davey, B. W. Mol, and D. L. Rolnik, "The Evolution of the Diagnostic Criteria of Preeclampsia-Eclampsia," Am. J. Obstet. Gynecol., vol. 226, pp. S835–S843, 2022.

G. Yerlikaya-Schatten et al., "Cardiac Function in Pregnant Women With Preeclampsia," Front. Cardiovasc. Med., vol. 11, p. 1415727, 2024.